Final autopsy results for Gene Hackman revealed the actor had a long history of serious medical issues, including congestive heart failure, advanced cardiovascular disease, and signs of Alzheimer's disease. Hackman had a bi-ventricular pacemaker, coronary stents, a bypass graft, and an aortic valve replacement. His brain showed microscopic signs of advanced Alzheimer's. Although his wife, Betsy Arakawa, died from hantavirus—a rare rodent-borne illness—Hackman tested negative for the virus. Authorities believe Arakawa, who was 65, died first around February 12, before Hackman was also found dead in their New Mexico home.