Matthew McConaughey and Woody Harrelson are teaming up again for Brothers, an eight-episode comedy premiering September 23 on Apple TV+. The longtime friends play fictionalized versions of themselves whose lives are thrown into chaos after discovering they may actually be brothers—a storyline inspired by real-life speculation about their family ties. The series follows the two as they unravel the mystery while McConaughey also considers a run for governor of Texas, blending comedy with family drama and plenty of self-aware humor.