Rob Reiner, the influential actor, director, and producer whose work helped define modern American film and television, has died at age 78, according to reports from Variety and TMZ. His death, along with that of his wife, photographer Michele Singer, 68, is currently under investigation by the Los Angeles Police Department after the couple was found deceased in their Brentwood, California, home. Reiner was entertainment royalty—the son of comedy legend Carl Reiner and actress Estelle Reiner. He first rose to fame as Michael “Meathead” Stivic on the groundbreaking sitcom All in the Family, earning two Emmy Awards for his role as Archie Bunker’s outspoken son-in-law. Reiner later transitioned behind the camera and became one of Hollywood’s most respected directors, helming an extraordinary run of classics including This Is Spinal Tap, Stand by Me, The Princess Bride, When Harry Met Sally…, Misery, and A Few Good Men. One of his most famous moments came from When Harry Met Sally…, when he cast his mother in the iconic deli scene that ended with the immortal line, “I’ll have what she’s having.” This Is Spinal Tap became a cultural landmark and was later added to the Library of Congress’ National Film Registry. Reiner was previously married to actress and director Penny Marshall from 1971 to 1981 and adopted her daughter, Tracy. In 1989, he married Michele Singer, with whom he had three children: Nick, Jake, and Romy. He often credited Singer with inspiring the romantic ending of When Harry Met Sally…, which he was directing when they met.